AOD-9604

AOD-9604 Overview

AOD-9604 is a synthetic peptide fragment derived from the C-terminus of the somatotropin sequence (fragment 176–191, with an added N-terminal Tyr). It is studied for its effects on lipolytic and anti-lipogenic pathways, β3-adrenergic signaling, and downstream pathway dynamics in laboratory and preclinical models.

Heffernan M. et al. (2001).

History

Developed in the late 1990s/early 2000s as a focused hGH fragment, AOD-9604 was advanced into early clinical programs to investigate mechanism-driven metabolic effects and safety. Subsequent summaries report randomized, placebo-controlled trials evaluating IGF-1, glucose tolerance, and immunogenicity endpoints in research settings.

Stier H. et al. (2013).

AOD-9604 Structure

CAS #:

386264-39-7

Molecular Formula:

C₇₈H₁₂₃N₂₃O₂₃S₂

Molecular Weight:

1815.1 g/mol

PubChem ID:

71300630