Sermorelin

Sermorelin Overview

Sermorelin is a synthetic peptide analog of GHRH (1-29). It is studied in laboratory and preclinical models for its ability to modulate somatotroph axis signaling, thereby influencing downstream cascades and associated pathway activity. Research has focused on its role in endocrine modulation, molecular dynamics, and structural remodeling processes.

Walker R.F. et al. (1994).

History

Sermorelin was developed in the late 20th century as a stabilized fragment of GHRH (1-29), the biologically active portion of the endogenous peptide. Initial investigations focused on its pharmacokinetics and ability to activate pituitary signaling pathways. Since then, it has been used widely in experimental models to study endocrine dynamics, pathway activity, and age-associated changes in somatotroph axis signaling.

Walker R.F., Risher W.H. et al. (1994).

Sermorelin Structure

CAS #:

86168-78-7

Molecular Formula:

C₁₄₉H₂₄₆N₄₄O₄₂S

Molecular Weight:

3357.9 g/mol

PubChem ID:

16132308