TB-500

TB-500 Overview

TB-500 is a synthetic peptide fragment derived from thymosin beta-4, a naturally occurring protein studied for its role in molecular signaling and pathway dynamics. Research has focused on its potential influence on matrix remodeling, angiogenesis, and molecular migration in preclinical and laboratory models. TB-500 is of particular interest in investigations involving connective tissue, structural dynamics, and extracellular matrix pathways.

Goldstein A.L. et al. (2005).

History

Thymosin Beta-4, the parent protein of TB-500, was first isolated in the 1960s by Allan L. Goldstein and colleagues during research into thymus-derived peptides. TB-500 was later synthesized as a research fragment to enable focused study on Tβ4's signaling functions. Since its development, it has been investigated across models of angiogenesis, structural dynamics, and molecular migration, with growing interest in its systemic regulatory potential.

Goldstein A.L., Hannappel E. et al. (2012).

TB-500 Structure

CAS #:

77591-33-4

Molecular Formula:

C₂₁₂H₃₅₀N₅₆O₇₈S

Molecular Weight:

4963.5 g/mol

PubChem ID:

16132321