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Manufactured in USA
Third-party batch tested
Research Use Only
All products are intended solely for laboratory research and are not for human or animal consumption. By purchasing, the buyer agrees to use these products in compliance with all applicable laws.
MOTS-c was first described in 2015 following the discovery of short open reading frames encoded within mitochondrial DNA. Identified as a mitochondrial-derived peptide with signaling activity, it has since been studied for its ability to activate AMPK pathways and support molecular stress resistance. This discovery expanded the understanding of mitochondria as signaling organelles beyond energy production, positioning MOTS-c as a key peptide in mitochondrial biology research.
MOTS-c
CAS #: 1627580-64-6
Molecular Formula: C₁₄₉H₂₆₀N₄₆O₄₆S₂
Molecular Weight: 2171.5 g/mol
PubChem ID: 91808068
MOTS-c has been studied in mitochondrial, molecular, and systemic models, with research highlighting its role in mitochondrial function, AMPK pathway activation, and signaling dynamics. Studies also report activity in substrate utilization, downstream markers, and molecular stress responses in preclinical settings.
Key Areas of Research:
Mitochondrial: AMPK, signaling, pathway dynamics
Molecular: Mitochondrial function, stress response, remodeling
Systemic: Signaling, resilience, viability
Together, these findings suggest broad experimental potential for MOTS-c across mitochondrial, molecular, and systemic pathways. By engaging mitochondrial biology and modulating AMPK and stress response pathways, MOTS-c provides a versatile platform for research into pathway characterization, molecular dynamics, and systemic resilience in laboratory settings.
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